Whereas lower-rely MBL hardly ever progresses to CLL, large-rely MBL progresses to CLL demanding therapy in a price of one% to 2% annually. High-depend MBL is distinguished from Rai 0 CLL according to if the B-cell rely is previously mentioned or underneath five × 109/L. Whilst persons with the two higher-rely MBL and CLL Rai stage 0 are at enhanc